Ventricular Septal Defect
This is the single most common congenital cardiac abnormality
Anatomy
The Ventricular Septum (bit between the two ventricles) is made up of two parts the Membranous and Muscular parts respectively the former is the most common site for a Ventricular Septal Defect (VSD) but, if a VSD occurs in the muscular part it is likely to be more complex.
The neonate
In utero a large VSD can cause failure of the LEFT ventricle, this is because the RV has very high pressures in utero which will damage the left ventricle, signs apart from the murmurs discussed later will include Failure to Thrive, Tachypnoea and Hepatomegaly.
The Adult
1 |
In the neonate we said that there was a right-to-left shunt, what is likely to happen in you or I if we had a moderately sized hole inbetween our ventricles |
Murmur
2 |
Is the murmur going to be Systolic |
A small VSD will produce a much larger murmur than a large VSD which can be quite quiet, due to the larger pressure gradient.
A small VSD will produce a pan-systolic murmur, which will radiate to the axilla and the apex
A large VSD will produce a pan-systolic murmur, which may not radiate if it is quiet but will probably also show signs of ventricular hypertrophy.
The following is an example of a pan-systolic murmur caused by a VSD
Note
At the age of 3 over 30% of VSD in children will have spontaneously closed and many more by the age of 10 afterwhich if the VSD still persists surgery to close it is usually performed.